Product Datasheet
BRMS1 Rabbit mAb
Catalog Number: 77903
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Storage:
- Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
- Immunogen:
- A synthesized peptide derived from human BRMS1.
- reactivity:
- Human,Mouse,Rat
- appl_detail:
- IHC 1:50 - 1:200
- other_names:
- BRMS1; breast cancer metastasis-suppressor 1
- Purification:
- Affinity purification
- Background:
- This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
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