Product Datasheet  
CCDC98 Rabbit mAb  
Catalog Number: 77220  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Q6UWZ7
  • Form of Antibody：  
  • Storage：  
  • Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
  • Immunogen：  
  • A synthesized peptide derived from human CCDC98.
  • reactivity：  
  • Human
  • appl_detail：  
  • WB 1:500 - 1:2000
    IP 1:50 - 1:200
  • other_names：  
  • FAM175A; ABRA1; CCDC98; BRCA1-A complex subunit Abraxas
  • Purification：  
  • Affinity purification
  • Specificity：  
  • Applications：  
  • WB,IP
  • Background：  
  • This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants.



 
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