Product Datasheet  
β-Catenin Antibody  
Catalog Number: 47993  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q02248
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu,Ms,Rt, zebrafish
  • appl_detail：  

  • WB 1:1,000

    ICC: 1:200

  • other_names：  
  • Beta catenin antibody
    Beta-catenin antibody
    Cadherin associated protein antibody
    Catenin (cadherin associated protein), beta 1, 88kDa antibody
    Catenin beta 1 antibody
    Catenin beta-1 antibody
    CATNB antibody
  • Purification：  
  • Immunogen affinity purified
  • Specificity：  
  • Applications：  
  • WB, ICC, IHC
  • Background：  

  • β-Catenin is a multifunctional adaptor protein involved in cadherin-mediated cellCcell adhesion and in responding to the activation of several signal transduction pathways. CK1 phosphorylates β-catenin on Ser45. This phosphorylation event primes β-catenin for subsequent phosphorylation by GSK-3. GSK-3β destabilizes β-catenin by phosphorylating it at Ser33, Ser37 and Thr41.). Mutations in β-Catenin have been implicated in its accumulation and various forms of carcinomas.




 
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