Product Datasheet  
Mouse anti Human CD163, APC Conjugated mAb  
Catalog Number: 28298  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Form of Antibody：  
  • Storage：  
  • Store at 4°C. DO NOT FREEZE. LIGHT SENSITIVE MATERIAL.
  • Immunogen：  
  • reactivity：  
  • Human, Not yet tested in other species.
  • appl_detail：  

  • Format: APC

    Vol.per.Test: 20 μl to 5 μl per test

    Storage Buffer: Phosphate-buffered solution, pH 7.4, containing 0.09% sodium azide and 0.2% (w/v) BSA

  • other_names：  
  • Purification：  
  • Specificity：  
  • Applications：  
  • FC
  • Background：  

  •  CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as 4AGHI/61, M130,RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD(non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases. 




 
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