Product Datasheet
Lumican Antibody
Catalog Number: 49986
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P51884
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein within human Lumican aa 50-250.
- appl_detail:
- WB: 1:500-1:2,000
IHC: 1:50-1:200
ICC: 1:50-1:200
FC: 1:50-1:100
- other_names:
- Keratan sulfate proteoglycan lumican antibody
KSPG lumican antibody
LDC antibody
LUM antibody
LUM_HUMAN antibody
Lumican antibody
Lumican precursor antibody
SLRR2D antibody
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IHC,FC
- Background:
- Lumican, a member of the small leucine-rich proteoglycans (SLRPs) family of proteins, is a keratan sulfate proteoglycan present in large quantities in the corneal stroma and in interstitial collagenous matrices of the heart, aorta, skeletal muscle, skin, and intervertebral discs. During collagen fibrillogenesis, lumican regulates the assembly of collagens into higher order fibrils, limiting the growth of fibrils in diameter. Lumican is present in the extracellular matrix of human articular cartilage at all ages, with a far greater abundance in the adult. The gene encoding human lumican maps to chromosome 12q21.3-q22.
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