Product Datasheet  
TTC11 Antibody  
Catalog Number: 49980  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q9Y3D6
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500-1:2,000
    IHC: 1:50-1:200
    ICC: 1:50-1:200

  • other_names：  
  • 2010003O14Rik antibody
    CGI 135 antibody
    CGI135 antibody
    FIS 1 antibody
    FIS1 antibody
    Fis1 homolog antibody
    FIS1, S. cerevisiae, homolog of antibody
    FIS1_HUMAN antibody
    Fission 1 (mitochondri
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,ICC,IF,IHC
  • Background：  
  • Fis1 localizes to the outer mitochondrial membrane and, along with dynamin-related protein (Drp1), participates in mitochondrial fission. Fission and fusion mechanisms regulate mitochondrial morphology within the cell. Fission frequency is determined by the level of Fis1 molecules at the mitochondrial surface. Fis1 contains a C-terminal domain, which is required for mitochondrial localization, and an N-terminal domain, which is necessary for mitochondrial fission. Fragmentation of the mitochondrial network by Fis1 leads to cytochrome c release and apoptosis. The mitochondrial fission mechanisms may be involved in positively and negatively regulating apoptosis.



 
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