Product Datasheet
Syntenin Antibody
Catalog Number: 49977
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O00560
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein within human Syntenin aa 1-200.
- appl_detail:
- WB: 1:500-1:2,000
IHC: 1:50-1:200
ICC/IF: 1:50-1:200
IP: 1:10-1:50
FC: 1:50-1:200
- other_names:
- MDA-9 antibody
MDA9 antibody
Melanoma differentiation-associated protein 9 antibody
Pro-TGF-alpha cytoplasmic domain-interacting protein 18 antibody
Scaffold protein Pbp1 antibody
SDCB1_HUMAN antibody
SDCBP anti
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IF,IHC,FC,IP
- Background:
- Syntenin-1 (also known as syntenin, syndecan binding protein, melanoma differentiation-associated protein 9 or proTGF-alpha cytoplasmic domain-interacting protein 18) is a protein that binds to the cytoplasmic domains of the syndecans in yeast 2-hybrid screens and other assays. Syntenin-1 contains a tandem repeat of PDZ domains that reacts with the FYA (phe-tyr-ala) carboxy-terminal amino acid sequence of the syndecans. It may function as an adaptor that couples syndecans to cytoskeletal proteins or cytosolic downstream signal-effectors. Syntenin-1 colocalizes and interacts specifically with immature, intracellular forms of proTGF-alpha. It is a human gamma interferon responsive protein. Syntenin-1 contains PSD-95/Discs large/zO-1 (PDZ) domains and associates with the cytoplasmic tail of the IL-5Ralpha. It directly associates with the transcription factor Sox-4. The PDZ proteins PICK1, GRIP, ABP and syntenin-1 bind multiple glutamate receptor subtypes.
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