Product Datasheet  
TNPO3 Antibody  
Catalog Number: 49947  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q9Y5L0
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:500-1:2,000
    IHC: 1:50-1:200
    ICC: 1:50-1:200

  • other_names:  
  • TNPO 3 antibody
    Imp12 antibody
    Importin 12 antibody
    Importin-12 antibody
    IPO12 antibody
    MTR10A antibody
    TNPO3 antibody
    TNPO3_HUMAN antibody
    Transportin 3 antibody
    Transportin SR antibo
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB,ICC,IF,IHC
  • Background:  
  • The Importin complex consists of Importin-α and Importin-β proteins which assist in transport of arginine- or serine-rich (SR) proteins across the nucleus. Importin-12, also known as Transportin-3 or Transportin-SR, is a member of the Importin-β family and functions as a nuclear transport receptor for serine/arginine-rich proteins. Through recognition of phosphorylated RS domains, Importin-12 mediates the nuclear import of several SR proteins, such as splicing factors SFRS1 and SFRS2. By regulating the nucleocytoplasmic transport of these and other SR mRNA splicing factors, Importin-12 controls their access to mRNA and, therefore, acts a transcriptional regulator.



 
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