Product Datasheet
TNPO3 Antibody
Catalog Number: 49947
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q9Y5L0
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- appl_detail:
- WB: 1:500-1:2,000
IHC: 1:50-1:200
ICC: 1:50-1:200
- other_names:
- TNPO 3 antibody
Imp12 antibody
Importin 12 antibody
Importin-12 antibody
IPO12 antibody
MTR10A antibody
TNPO3 antibody
TNPO3_HUMAN antibody
Transportin 3 antibody
Transportin SR antibo
- Purification:
- ProA affinity purified
- Applications:
- WB,ICC,IF,IHC
- Background:
- The Importin complex consists of Importin-α and Importin-β proteins which assist in transport of arginine- or serine-rich (SR) proteins across the nucleus. Importin-12, also known as Transportin-3 or Transportin-SR, is a member of the Importin-β family and functions as a nuclear transport receptor for serine/arginine-rich proteins. Through recognition of phosphorylated RS domains, Importin-12 mediates the nuclear import of several SR proteins, such as splicing factors SFRS1 and SFRS2. By regulating the nucleocytoplasmic transport of these and other SR mRNA splicing factors, Importin-12 controls their access to mRNA and, therefore, acts a transcriptional regulator.
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