Product Datasheet  
NOXA2 Antibody  
Catalog Number: 49940  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P19878
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein within Human NOXA2 aa 150-300.
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:500
    IHC: 1:50-1:200

    IP: 1:10-1:50
  • other_names：  
  • 67 kDa neutrophil oxidase factor antibody
    Chronic granulomatous disease autosomal 2 antibody
    FLJ93058 antibody
    NADPH oxidase activator 2 antibody
    NCF-2 antibody
    Ncf2 antibody
    NCF2_HUMAN antibody
    Neutroph
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,IHC,IP
  • Background：  
  • The heredity disease chronic granulomatous disease (CGF) has been linked to mutations in p47phox and p67phox. The cytosolic proteins p47phox and p67phox, also designated neutrophil cytosol factor 1(NCF1) and NCF2, respectively, are required for activation of the superoxide-producing NADPH oxidase in neutrophils and other phagocytic cells. During activation of the NADPH oxidase, p47phox and p67phox migrate to the plasma membrane where they associate with cytochrome b558 and the small G protein Rac to form the functional enzyme complex. Both p47phox and p67phox contain two Src homology 3 (SH3) domains. The C-terminal SH3 domain of p67phox has been shown to interact with the proline rich domain of p47phox, suggesting that p47phox may faciliate the transport of p67phox to the membrane.



 
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