Product Datasheet  
SAE1 Antibody  
Catalog Number: 49894  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q9UBE0
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein within human SAE1 aa 150-300.
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500-1:2,000



    FC: 1:50-1:100
  • other_names：  
  • Activator of SUMO1 antibody
    AOS1 antibody
    HSPC140 antibody
    Sae1 antibody
    SAE1_HUMAN antibody
    Sentrin/SUMO activating protein AOS1 antibody
    SUA1 antibody
    SUMO 1 activating enzyme E1 N subunit antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,FC
  • Background：  
  • Proteolytic degradation by the ubiquitin (Ub) system is essential for normal cell cycle progression, cellular differentiation and stress responses. Proteins conjugated to Ub are marked for progressive degradation by the 26S Proteasome. AOS-1, also designated SUMO-1-activating enzyme or ubiquitin-like 1-activating enzyme E1A, belongs to the ubiquitin-activating E1 family of proteins and plays an important role in the first step of the UBL1 conjugation pathway. AOS-1, which is a dimeric enzyme, functions as a UBLI E1 ligase, mediating the ATP-dependent activation of UBL1. AOS-1 can bind with UBLE1A and UBLE1B to form a heterodimer which can bind UBL1.



 
© Signalway Biotechnology All Rights Reserved.