Product Datasheet  
Pumilio 1 Antibody  
Catalog Number: 49885  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q14671
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein within human Pumilio 1 aa 1-200.
  • reactivity：  
  • Hu, Ms
  • appl_detail：  
  • WB: 1:1,000-1:2,000
    IHC: 1:50-1:200
    ICC: 1:50-1:200
    IP: 1:10-1:50
    FC: 1:50-1:100
  • other_names：  
  • HsPUM antibody
    KIAA0099 antibody
    PUM 1 antibody
    PUM L1 antibody
    Pum1 antibody
    PUM1_HUMAN antibody
    PUMH 1 antibody
    PUMH antibody
    PUMH1 antibody
    pumilio homolog 1 (Drosophila) antibod
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,ICC,IF,IHC,FC,IP
  • Background：  
  • Sequence-specific RNA-binding protein that acts as a post-transcriptional repressor by binding the 3'-UTR of mRNA targets. Binds to an RNA consensus sequence, the Pumilio Response Element (PRE), 5'-UGUANAUA-3', that is related to the Nanos Response Element (NRE). Mediates post-transcriptional repression of transcripts via different mechanisms: acts via direct recruitment of the CCR4-POP2-NOT deadenylase leading to translational inhibition and mRNA degradation. Also mediates deadenylation-independent repression by promoting accessibility of miRNAs.



 
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