Product Datasheet
Thrombomodulin Antibody
Catalog Number: 49869
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P07204
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500-1:2,000
IHC: 1:50-1:200
IP: 1:10-1:50
- other_names:
- AHUS 6 antibody
AHUS6 antibody
BDCA 3 antibody
BDCA3 antibody
CD 141 antibody
CD141 antibody
CD141 antigen antibody
Fetomodulin antibody
Thbd antibody
THPH12 antibody
THRM ant
- Purification:
- ProA affinity purified
- Background:
- Thrombomodulin (TM), also called CD141, is a type I membrane receptor that is specific to endothelial cells. TM has a cysteine-rich extracellular domain with six EGF-like regions. It forms a complex with Thrombin, which activates Protein C to generate activated Protein C (APC), an anticoagulant enzyme. APC together with Protein S inhibits coagulation by inactivating Factors Va and VIIIa. Deletion of the TM gene results in embryonic lethality in mice.
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