Product Datasheet  
H Cadherin Antibody  
Catalog Number: 49857  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P55290
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein within human H Cadherin aa 1-200.
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  

  • IHC: 1:50-1:200


  • other_names：  
  • CAD13_HUMAN antibody
    Cadherin-13 antibody
    CDH13 antibody
    CDHH antibody
    H-cadherin antibody
    Heart cadherin antibody
    P105 antibody
    T cad antibody
    T Cadherin antibody
    T-cad antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • IHC,WB
  • Background：  
  • Cadherins comprise a family of Ca++-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogen-esis. Cadherins each contain a large extracellular domains characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short intracellular domains interact with a variety of cytoplasmic proteins, such as β-catenin, to regulate cadherin function. T-cadherin (for truncated-cadherin), also designated heart-cadherin or cadherin-13) expression levels have been shown to be reduced in human breast cancers and carcinoma cell lines. Evidence suggests that decreased levels of T-cadherin indicate a progression in breast malignancies.



 
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