Product Datasheet
STIP1 Antibody
Catalog Number: 49844
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P31948
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500-1:1,000
IHC: 1:50-1:200
ICC: 1:50
FC: 1:50-1:100
- other_names:
- Epididymis secretory sperm binding protein Li 94n antibody
HEL S 94n antibody
Hop antibody
Hsc70/Hsp90 organizing protein antibody
Hsc70/Hsp90-organizing protein antibody
IEF SSP 3521 antibody
NY REN 11 antigen
- Purification:
- ProA affinity purified
- Applications:
- WB,IHC,FC,IP,ICC
- Background:
- Stress-induced-phosphoprotein 1 (STI1) functions as a co-chaperone for HSP70 and HSP90 during heat shock response. STI1 exists as either a monomer or a dimer, and this conformational flexibility facilitates its function in organizing HSP70/HSP90. HSP90 acts as an ATPase, and requires the recruitment of client proteins and proper conformation to function. STI1 acts as a "scaffold" for client protein recruitment to the relaxed, ADP-bound conformation of HSP90, thus suppressing ATP turnover during the loading phase and allowing proper function.
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