Product Datasheet  
CRM1 Antibody  
Catalog Number: 49809  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:O14980
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein within C terminal human CRM1.
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:500
    IHC: 1:50-1:100
    ICC: 1:50-1:200

    FC: 1:50-1:100
  • other_names：  
  • Chromosome region maintenance 1 protein homolog antibody
    CRM 1 antibody
    CRM1 homolog antibody
    DKFZp686B1823 antibody
    emb antibody
    Exp 1 antibody
    Exp1 antibody
    Exportin 1 antibody
    Exportin-1 anti
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,ICC,IF,IHC,FC
  • Background：  
  • Protein transport across the nucleus is a selective, multistep process involving several cytoplasmic factors. Proteins must be recognized as import substrates, dock at the nuclear pore complex and translocate across the nuclear envelope in an ATP-dependent fashion. Two cytosolic factors centrally involved in the recognition and docking process are the karyopherin alpha1 and karyopherin beta1 subunits. p62 glycoprotein is a nucleoporin that is not only involved in the nuclear import of proteins, but also the export of nascent mRNA strands. NTF2 (nuclear transport factor 2) interacts with nucleoporin p62 as a homodimer composed of two monomers, and may be an obligate component of functional p62. CRM1 has been shown to be an export receptor for leucine-rich proteins that contain the nuclear export signal (NES).



 
© Signalway Biotechnology All Rights Reserved.