Product Datasheet  
PBK Antibody  
Catalog Number: 48483  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q96KB5
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500
    IHC: 1:100-1:500
    ICC: 1:100-1:500

    FC: 1:100-1:200
  • other_names：  
  • Cancer/testis antigen 84 antibody
    CT84 antibody
    Epididymis luminal protein 164 antibody
    FLJ14385 antibody
    HEL164 antibody
    Lymphokine activated killer T cell originated protein kinase antibody
    Lymphokine-activated killer T-cell-originated protein kinase antibody
    MAPKK like protein kinase antibody
    MAPKK-like protein kinase antibody
    Nori 3 antibody
    Nori-3 antibody
    Nori3 antibody
    PBK antibody
    PDZ binding kinase antibody
    PDZ-binding kinase antibody
    Serine/threonine protein kinase antibody
    Spermatogenesis related protein kinase antibody
    Spermatogenesis-related protein kinase antibody
    SPK antibody
    T LAK cell originated protein kinase antibody
    T-LAK cell-originated protein kinase antibody
    TOPK antibody
    TOPK_HUMAN antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,ICC,IHC,FC
  • Background：  
  • Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Kinases are capable of influencing the oncogenic potential of cell sytems at the level of oncoprotein or tumor suppressor protein phosphorylation states. Human PDZ-binding kinase, known as PBK, is a 322 amino acid, T/SXV motif-containing serine/threonine kinase that is abuntant in placenta and absent from adult brain tissue. A PDZ domain in the tumor suppressor protein Dlg can coordinate with the T/SXV motif of PBK. The cell cycle checkpoint kinase Cdc2/cyclin B is an upstream effector of PBK that can phosphorylate and activate PBK. Active PBK may associate with PDZ-containing proteins and influence cell cycle control or cellular proliferation.



 
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