Product Datasheet
CD94 Antibody
Catalog Number: 48471
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q13241
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500-1:1,000
FC: 1:100-1:200
- other_names:
- CD 94 antibody
CD94 antibody
CD94 antigen antibody
Killer cell lectin like receptor subfamily D member 1 antibody
Killer cell lectin-like receptor subfamily D member 1 antibody
KLRD 1 antibody
KLRD1 antibody
KLRD1 protein antibody
KLRD1_HUMAN antibody
KP 43 antibody
KP43 antibody
Natural killer cells antigen CD94 antibody
NK cell receptor antibody
OTTHUMP00000238754 antibody
OTTHUMP00000238755 antibody
OTTHUMP00000238756 antibody
OTTHUMP00000238758 antibody
OTTHUMP00000239093 antibody
- Purification:
- ProA affinity purified
- Background:
- The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The KIR/LIR family includes p91A and p91B (also designated PIR-A). p91A acts as an inhibitory receptor through interactions with SHP-1, whereas p91B acts as an activating receptor (3-4). CD94, NKG2 and Ly-49 are members of the C-type lectin superfamily of type II membrane glycoproteins. CD94 forms heterodimers with NKG2 isoforms on the surface of NK cells, whereas Ly-49 isoforms form homodimers. NKG2-D, expressed on NK cells, gdT cells, and CD8+ αβ T cells, is a receptor for the stress inducible protein MICA, an antigen frequently expressed in epithelial tumors.
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