Product Datasheet  
CD94 Antibody  
Catalog Number: 48471  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Mouse
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q13241
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB: 1:500-1:1,000



    FC: 1:100-1:200
  • other_names:  
  • CD 94 antibody
    CD94 antibody
    CD94 antigen antibody
    Killer cell lectin like receptor subfamily D member 1 antibody
    Killer cell lectin-like receptor subfamily D member 1 antibody
    KLRD 1 antibody
    KLRD1 antibody
    KLRD1 protein antibody
    KLRD1_HUMAN antibody
    KP 43 antibody
    KP43 antibody
    Natural killer cells antigen CD94 antibody
    NK cell receptor antibody
    OTTHUMP00000238754 antibody
    OTTHUMP00000238755 antibody
    OTTHUMP00000238756 antibody
    OTTHUMP00000238758 antibody
    OTTHUMP00000239093 antibody
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • WB,FC
  • Background:  
  • The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The KIR/LIR family includes p91A and p91B (also designated PIR-A). p91A acts as an inhibitory receptor through interactions with SHP-1, whereas p91B acts as an activating receptor (3-4). CD94, NKG2 and Ly-49 are members of the C-type lectin superfamily of type II membrane glycoproteins. CD94 forms heterodimers with NKG2 isoforms on the surface of NK cells, whereas Ly-49 isoforms form homodimers. NKG2-D, expressed on NK cells, gdT cells, and CD8+ αβ T cells, is a receptor for the stress inducible protein MICA, an antigen frequently expressed in epithelial tumors.



 
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