Product Datasheet  
PSIP1 Antibody  
Catalog Number: 48469  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:O75475
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu, Monkey, Rt
  • appl_detail：  
  • WB: 1:500-1:1,000
    IHC: 1:100-1:500
    ICC: 1:100-1:500

  • other_names：  
  • CLL associated antigen KW 7 antibody
    CLL-associated antigen KW-7 antibody
    Dense fine speckles 70 kDa protein antibody
    DFS 70 antibody
    DFS70 antibody
    LEDGF antibody
    Lens epithelium derived growth factor antibody
    Lens epithelium-derived growth factor antibody
    MGC74712 antibody
    p52 antibody
    p75 antibody
    PAIP antibody
    PC4 and SFRS1 interacting protein 1 antibody
    PC4 and SFRS1 interacting protein 2 antibody
    PC4 and SFRS1 interacting protein antibody
    PC4 and SFRS1-interacting protein antibody
    PSIP 1 antibody
    PSIP 2 antibody
    Psip1 antibody
    PSIP1_HUMAN antibody
    PSIP2 antibody
    Transcriptional coactivator p75/p52 antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,ICC,IHC
  • Background：  
  • PSIP1 (PC4 and SFRS1 interacting protein 1), also known as CLL-associated antigen KW-7, PSIP2, LEDGF (lens epithelium-derived growth factor), PAIP, DFS70 (dense fine speckles 70 kDa protein) or transcriptional coactivator p75/p52, is a 530 amino acid nuclear protein that associates with chromatin throughout the cell cycle. Functioning as a transcriptional coactivator that complexes with the human immunodeficiency virus type 1 (HIV-1) integrase, PSIP1 is essential for the nuclear localization and chromosomal association of viral proteins. As the primary integrase-to-chromatin tethering factor for HIV-1, PSIP1 is responsible for the cellular trafficking of lentiviral integrases. During apoptosis, PSIP1 is cleaved at three sites by caspase-3 and caspase-7, contributing to the pathogenesis of atopic disorders.



 
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