Product Datasheet  
SMAD6 Antibody  
Catalog Number: 48465  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:O43541
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500-1:1,000



  • other_names：  
  • hSMAD6 antibody
    MAD homolog 6 antibody
    MADH6 antibody
    MADH7 antibody
    Mothers against decapentaplegic homolog 6 antibody
    Mothers against DPP homolog 6 antibody
    SMAD 6 antibody
    SMAD family member 6 antibody
    SMAD mothers against DPP homolog 6 antibody
    Smad6 antibody
    SMAD6_HUMAN antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB
  • Background：  
  • Smad proteins, the mammalian homologs of the Drosophila Mothers against dpp (Mad) have been implicated as downstream effectors of TGFβ/BMP signaling. Smad1 (also designated Madr1 or JV4-1), Smad5 and mammalian Smad8 (also designated Smad9 or MADH6) are effectors of BMP2 and BMP4 function while Smad2 (also designated Madr2 or JV18-1) and Smad3 are involved in TGFβ and activin-mediated growth modulation (2-5,8). Smad4 (also designated DPC4) has been shown to mediate all of the above activities through interaction with various Smad family members. Smad6 and Smad7 regulate the response to activin/TGFβ signaling by interfering with TGFβ-mediated phosphorylation of other Smad family members.



 
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