Product Datasheet  
THAP1 Antibody  
Catalog Number: 48420  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q9NVV9
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500-1:2,000

    ICC: 1:50-1:200

    FC: 1:50-1:200
  • other_names：  
  • 4833431A01Rik antibody
    DYT6 antibody
    FLJ10477 antibody
    MGC33014 antibody
    Nuclear proapoptotic factor antibody
    THAP 1 antibody
    THAP domain containing 1 antibody
    THAP domain containing apoptosis associated protein 1 antibody
    THAP domain containing protein 1 antibody
    THAP domain protein 1 antibody
    THAP domain-containing protein 1 antibody
    Thap1 antibody
    THAP1_HUMAN antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, ICC, FC
  • Background：  
  • THAP1 (THAP domain containing, apoptosis associated protein 1) is a 213 amino acid protein that localizes to the nucleoplasm and contains one THAP-type zinc finger, a conserved DNA-binding domain. Interacting with PAR4, THAP1 functions as a pro-apoptotic protein that acts in a zinc-dependent manner and enhances the likelihood of both TNF- and serum withdrawal-induced apoptosis, possibly playing a role in promyelocytic leukemia. The gene encoding THAP1 maps to human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8.



 
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