Product Datasheet  
DHX58 Antibody  
Catalog Number: 48413  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q96C10
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500-1:2,000



    FC: 1:50-1:200
  • other_names：  
  • D11LGP2 antibody
    D11lgp2e antibody
    DEXH (Asp Glu X His) box polypeptide 58 antibody
    DEXH box polypeptide 58 antibody
    DHX 58 antibody
    DHX58 antibody
    DHX58_HUMAN antibody
    LGP 2 antibody
    LGP2 antibody
    Ortholog of mouse D11lgp2 antibody
    Probable ATP dependent helicase LGP2 antibody
    Probable ATP dependent RNA helicase DHX58 antibody
    Probable ATP-dependent helicase LGP2 antibody
    Probable ATP-dependent RNA helicase DHX58 antibody
    Protein D11Lgp2 homolog antibody
    RIG-I-like receptor LGP2 antibody
    RLR antibody
    RNA helicase LGP2 antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, FC
  • Background：  
  • Helicases are enzymes that catalyze the separation of double stranded DNA or RNA by utilizing ATP. LGP2, also known as probable ATP-dependent RNA helicase DHX58, is a 678 amino acid protein belonging to the helicase family. LGP2 acts as a negative regulator of host innate immune defense against viruses by binding dsRNA produced during viral replication. The repressor domain of LGP2 binds to RIG-I, a signaling protein involved in host defenses against hepatitis C virus (HCV). By preventing RIG-I multimerization, LGP2 negatively regulates RIG-I-mediated signaling. Localized to the cytoplasm, LGP2 contains one helicase ATP-binding domain and one helicase C-terminal domain.



 
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