Product Datasheet
CD168 Antibody
Catalog Number: 48409
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:O75330
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein
- appl_detail:
- WB: 1:500-1:2,000
FC: 1:50-1:100
- other_names:
- CD168 antibody
CD168 antigen antibody
HMMR antibody
HMMR_HUMAN antibody
Hyaluronan mediated motility receptor antibody
Hyaluronan-mediated motility receptor (RHAMM) antibody
IHABP antibody
Intracellular hyaluronic acid-binding protein antibody
MGC119494 antibody
MGC119495 antibody
OTTHUMP00000196920 antibody
Receptor for hyaluronan-mediated motility antibody
RHAMM antibody
- Purification:
- ProA affinity purified
- Background:
- Hyaluronic acid (HA) is a nonsulfated glycosaminoglycan that regulates cell adhesion and migration. HA effects are mediated through two receptors, CD44 (also designated HCAM) and the receptor of hyaluronic acid mediated motility (RHAMM). RHAMM, also designated intracellular hyaluronic acid binding protein (IHABP) and CD168, is a matrix receptor, which is linked to the plasma membrane by a GPI anchor and regulates cell motility. RHAMM expression is upregulated in malignant lymphoid tissues and is subsequently implicated in tumor progression and metastasis formation, as well as signal transduction. Although still unclear, RHAMM is thought to exist as several isoforms ranging in size. A variant isoform, designated v4, is a protein that when over-expressed, is thought to be the cause of transformation and metastasis formation in fibroblasts
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