Product Datasheet  
CHRNA7 Antibody  
Catalog Number: 48396  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P36544
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:500-1:2,000
    IHC: 1:50-1:200


    FC: 1:50-1:100
  • other_names：  
  • 7nAChR antibody
    a7 nicotinic acetylcholine receptor antibody
    acetylcholine receptor, neuronal nicotinic, alpha-7 subunit antibody
    ACHA7_HUMAN antibody
    AChR antibody
    Acra7 antibody
    alpha 7 neuronal nicotinic acetylcholine receptor antibody
    alpha-7 nicotinic cholinergic receptor subunit antibody
    alpha7 antibody
    cholinergic receptor, neuronal nicotinic, alpha polypeptide 7 antibody
    cholinergic receptor, nicotinic, alpha 7 (neuronal) antibody
    cholinergic receptor, nicotinic, alpha 7 antibody
    cholinergic receptor, nicotinic, alpha polypeptide 7 antibody
    CHRNA7 antibody
    CHRNA7-2 antibody
    NACHRA7 antibody
    neuronal acetylcholine receptor protein, alpha-7 chain antibody
    Neuronal acetylcholine receptor subunit alpha-7 antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IHC, FC
  • Background：  
  • Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. Glutamate receptors are found in the postsynaptic membrane of cells in the central nervous system. The activity that is generated at the synapse by the binding of acetylcholine is terminated by acetylcholinesterase, an enzyme that rapidly hydrolyzes acetylcholine. AChRα7, also known as NACHRA7, CHRNA7-2 or CHRNA7, is a 502 amino acid multi-pass membrane protein existing as a homopentamer and interacts with RIC-3, a nicotinic acetylcholine receptor (nAChR)-associated protein.



 
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