Product Datasheet  
TSH Antibody  
Catalog Number: 48381  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Mouse
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P01215
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.23% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu, Ms
  • appl_detail:  
  • WB: 1:1,000
    IHC: 1:50-1:200
    ICC: 1:50-1:200

  • other_names:  
  • CG ALPHA antibody
    CGA antibody
    Chorionic gonadotropin alpha polypeptide antibody
    FSHA antibody
    Glycoprotein hormones alpha polypeptide antibody
    GPHA1 antibody
    Thyroid stimulating hormone beta subunit antibody
    Thyrotropin beta subunit antibody
    TSH beta antibody
    TSHA antibody
    TSHB antibody
  • Purification:  
  • Specificity:  
  • Applications:  
  • WB, IHC, ICC
  • Background:  
  • Various hormones are secreted from the anterior pituitary during development and growth, including thyroid-stimulating hormone (TSH, also known as thyrotropin), follicle-stimulating hormone (FSH) and leutinizing hormone (LH). TSH, FSH, and LH are heterodimers formed from a common α chain and a unique β chain. TSH is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSHβ is regulated by thyroid hormone (T3) and various retinoid compounds. TSHβ binds to the thyroid-stimulating hormone receptor (TSHR), which plays a major role in regulating thyroid function. TSHR is thought to exist in multiple glycosylation states. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation.



 
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