Product Datasheet
EP-CAM Antibody
Catalog Number: 48359
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P16422
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- recombinant protein
- appl_detail:
- WB: 1:1,000-1:2,000
IHC: 1:200-1:500
ICC: 1:100-1:200
FC: 1:100-1:200
- other_names:
- 17 1A antibody
323/A3 antibody
Adenocarcinoma associated antigen antibody
Adenocarcinoma-associated antigen antibody
Antigen identified by monoclonal antibody
AUA1 antibody
AUA1 antibody
CD326 antibody
CD326 antigen antibody
Cell surface glycoprotein Trop 1 antibody
Cell surface glycoprotein Trop 2 antibody
Cell surface glycoprotein Trop-1 antibody
CO 17A antibody
CO17 1A antibody
CO17A antibody
DIAR5 antibody
EGP 2 antibody
EGP antibody
EGP2 antibody
EGP314 antibody
EGP40 antibody
Ep CAM antibody
Ep-CAM antibody
EPCAM antibody
EPCAM_HUMAN antibody
EpCAM1 antibody
Epithelial cell adhesion molecule antibody
Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD) antibody
Epithelial cell surface antigen antibody
Epithelial cellular adhesion molecule antibody
Epithelial glycoprotein 1 antibody
Epithelial glycoprotein 314 antibody
Epithelial glycoprotein antibody
ESA antibody
GA733 1 antibody
GA733 2 antibody
GA733-2 antibody
gastrointestinal tumor-associated antigen 2, 35-KD glycoprotein antibody
gp4 antibody
hEGP 2 antibody
hEGP314 antibody
HNPCC8 antibody
Human epithelial glycoprotein 2 antibody
KS 1/4 antigen antibody
KS1/4 antibody
KSA antibody
Ly74 antibody
Lymphocyte antigen 74 antibody
M1S 1 antibody
M1S2 antibody
M4S1 antibody
Major gastrointestinal tumor associated protein GA733 2 antibody
Major gastrointestinal tumor-associated protein GA733-2 antibody
mEGP314 antibody
Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody
Membrane component, chromosome 4, surface marker 1 antibody
Membrane component, chromosome 4, surface marker antibody
MIC18 antibody
MK 1 antibody
Protein 289A antibody
TACD1 antibody
TACSTD1 antibody
TROP1 antibody
Tumor associated calcium signal transducer 1 antibody
Tumor associated calcium signal transducer 2 precursor antibody
Tumor-associated calcium signal transducer 1 antibody
- Purification:
- ProL affinity purified
- Applications:
- WB, ICC, IHC, FC
- Background:
- Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies. Mutations in EpCAM have also been associated with congenital tufting enteropathy which causes intractable diarrhea in newborn children. Specificity/Source: This antibody is produced by immunizing mice with recombinant protein corresponding to a region of EpCAM.
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