Product Datasheet  
EP-CAM Antibody  
Catalog Number: 48359  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Mouse
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P16422
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • recombinant protein
  • reactivity:  
  • Hu,Ms
  • appl_detail:  
  • WB: 1:1,000-1:2,000
    IHC: 1:200-1:500
    ICC: 1:100-1:200

    FC: 1:100-1:200
  • other_names:  
  • 17 1A antibody
    323/A3 antibody
    Adenocarcinoma associated antigen antibody
    Adenocarcinoma-associated antigen antibody
    Antigen identified by monoclonal antibody
    AUA1 antibody
    AUA1 antibody
    CD326 antibody
    CD326 antigen antibody
    Cell surface glycoprotein Trop 1 antibody
    Cell surface glycoprotein Trop 2 antibody
    Cell surface glycoprotein Trop-1 antibody
    CO 17A antibody
    CO17 1A antibody
    CO17A antibody
    DIAR5 antibody
    EGP 2 antibody
    EGP antibody
    EGP2 antibody
    EGP314 antibody
    EGP40 antibody
    Ep CAM antibody
    Ep-CAM antibody
    EPCAM antibody
    EPCAM_HUMAN antibody
    EpCAM1 antibody
    Epithelial cell adhesion molecule antibody
    Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD) antibody
    Epithelial cell surface antigen antibody
    Epithelial cellular adhesion molecule antibody
    Epithelial glycoprotein 1 antibody
    Epithelial glycoprotein 314 antibody
    Epithelial glycoprotein antibody
    ESA antibody
    GA733 1 antibody
    GA733 2 antibody
    GA733-2 antibody
    gastrointestinal tumor-associated antigen 2, 35-KD glycoprotein antibody
    gp4 antibody
    hEGP 2 antibody
    hEGP314 antibody
    HNPCC8 antibody
    Human epithelial glycoprotein 2 antibody
    KS 1/4 antigen antibody
    KS1/4 antibody
    KSA antibody
    Ly74 antibody
    Lymphocyte antigen 74 antibody
    M1S 1 antibody
    M1S2 antibody
    M4S1 antibody
    Major gastrointestinal tumor associated protein GA733 2 antibody
    Major gastrointestinal tumor-associated protein GA733-2 antibody
    mEGP314 antibody
    Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody
    Membrane component, chromosome 4, surface marker 1 antibody
    Membrane component, chromosome 4, surface marker antibody
    MIC18 antibody
    MK 1 antibody
    Protein 289A antibody
    TACD1 antibody
    TACSTD1 antibody
    TROP1 antibody
    Tumor associated calcium signal transducer 1 antibody
    Tumor associated calcium signal transducer 2 precursor antibody
    Tumor-associated calcium signal transducer 1 antibody
  • Purification:  
  • ProL affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC, IHC, FC
  • Background:  
  • Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies. Mutations in EpCAM have also been associated with congenital tufting enteropathy which causes intractable diarrhea in newborn children. Specificity/Source: This antibody is produced by immunizing mice with recombinant protein corresponding to a region of EpCAM.



 
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