Product Datasheet  
Chromogranin-A(C-term) Antibody  
Catalog Number: 48354  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P10645
  • Form of Antibody：  
  • 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Peptide
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:500
    IHC: 1:50-1:200
    ICC: 1:50-1:200

  • other_names：  
  • beta Granin antibody
    betagranin (N-terminal fragment of chromogranin A) antibody
    catestatin antibody
    CgA antibody
    CHG A antibody
    Chga antibody
    chromofungin antibody
    Chromogranin A antibody
    Chromogranin A parathyroid secretory protein 1 antibody
    Chromogranin A precursor antibody
    ChromograninA antibody
    CMGA_HUMAN antibody
    ER-37 antibody
    Pancreastatin antibody
    Parastatin antibody
    Parathyroid secretory protein 1 antibody
    Pituitary secretory protein I antibody
    Secretory protein I antibody
    SP I antibody
    SP-I antibody
    SP1 antibody
    SPI antibody
    Vasostatin antibody
    Vasostatin I antibody
    Vasostatin II antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB,IHC,ICC
  • Background：  
  • Chromogranins (secretogranins) are acidic glycoproteins that localize within secretory granules of endocrine, neuroendocrine and neuronal tissue. Family members include chromogranin A (Chr-A), chromogranin B (Chr-B, also known as secretogranin I) chromogranin C (also known as secretogranin II or Sg II), secretogranin III (Sg III or SCG3). High levels of Chr-A expression is a characteristic of neuroendocrine tumors. Pancreastatin is a peptide derived from Chr-A which inhibits insulin secretion, exocrine pancreatic secretion and gastric acid secretion. Pancreastatin exists as two forms; the major form is expressed in stomach and colon extracts. In neuroendocrine cells the level Sg II has been shown to increase four-fold in response to histamine, while levels of Chr-A and Chr-B showed little or no increase. Sg III is an acidic secretory protein expressed in neuronal and endocrine cells. In the anterior lobe of the rat pituitary gland, Sg III is present in mammotropes and thyrotropes, moderately in gonadotropes and corticotropes, though not in somatotropes. Sg III and carboxypeptidase E (CPE) bind specifically to cholesterol-rich secretory granule (SG) membranes.



 
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