Product Datasheet  
SFRP1 Antibody  
Catalog Number: 48337  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q5T4F7
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:100-1:1,000


    IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
  • other_names：  
  • Frizzled related protein 1 antibody
    FRP 1 antibody
    FRP antibody
    FRP-1 antibody
    FRP1 antibody
    FrzA antibody
    SARP 2 antibody
    SARP-2 antibody
    SARP2 antibody
    Secreted apoptosis related protein 2 antibody
    Secreted apoptosis-related protein 2 antibody
    Secreted frizzled related protein 1 antibody
    Secreted frizzled related protein antibody
    Secreted frizzled-related protein 1 antibody
    SFRP 1 antibody
    sFRP-1 antibody
    SFRP1 antibody
    SFRP1_HUMAN antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IP, IF
  • Background：  
  • The frizzled gene was originally identified in Drosophila melanogaster and was shown to be involved in the development of tissue polarity. The mammalian homolog of frizzled, as well as several mammalian frizzled-related proteins, FRP-1 (also designated SARP2), FRP-2 (also designated SARP1), FRP-3 and SARP3 (also designated FRP-5) have been identified. Frizzled is a transmem- brane protein that functions as a receptor for Wnt. The frizzled related proteins FRP-1, FRP-2, FRP-3 and SARP3 are secreted proteins that contain regions of homology to the cysteine-rich ligand-binding domain of frizzled. The FRPs/ SARPs have also been shown to be involved in the Wnt signaling pathway by regulating the intracellular levels of β-catenin.



 
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