Product Datasheet
Na+/K+ ATPase Antibody
Catalog Number: 48318
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.：
- Swiss-Prot#:P05023
- Form of Antibody：
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen：
- Amino acids 551-850 of Na+/K+-ATPase α1 of human origin.
- appl_detail：
- WB: 1:2,000-1:1,0000
IHC: 1:50-1:500
IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
- other_names：
- ATPase Na+/K+ transporting alpha antibody adenosinetriphosphatase antibody AT1A1_HUMAN antibody ATP1A1 antibody ATP1A4 antibody ATP1AL2 antibody ATP1B antibody ATP1B1 antibody ATPase Na+/K+ transporting alpha 1 polypeptide antibody ATPase Na+/K+ transporting alpha 4 polypeptide antibody ATPase Na+/K+ transporting beta 1 polypeptide antibody ATPase, Na+/K+ transporting, alpha polypeptide-like 2 antibody ATPase, Na+/K+ transporting, beta 1 polypeptide antibody Beta 1-subunit of Na(+),K(+)-ATPase antibody Na(+)/K(+) ATPase alpha-1 subunit antibody Na(+)/K(+) ATPase alpha-4 subunit antibody Na+, K+ ATPase alpha subunit antibody Na+/K+ ATPase 1 antibody Na+/K+ ATPase 4 antibody Na+/K+ ATPase, alpha-D polypeptide antibody Na, K-ATPase beta-1 polypeptide antibody Na, K-ATPase, alpha-A catalytic polypeptide antibody Na,K-ATPase catalytic subunit alpha-A protein antibody Na,K-ATPase subunit alpha-C antibody polypeptide-like 2 antibody Sodium pump 1 antibody sodium pump 4 antibody Sodium pump subunit alpha-1 antibody sodium pump subunit alpha-4 antibody sodium pump subunit beta-1 antibody sodium-potassium ATPase catalytic subunit alpha-1 antibody sodium-potassium ATPase catalytic subunit alpha-4 antibody sodium-potassium ATPase subunit beta 1 (non-catalytic) antibody sodium-potassium ATPase, alpha 4 polypeptide antibody sodium-potassium-ATPase, alpha 1 polypeptide antibody Sodium/potassium transporting ATPase alpha 1 chain antibody Sodium/potassium transporting ATPase subunit beta 1 antibody sodium/potassium-dependent ATPase beta-1 subunit antibody sodium/potassium-transporting ATPase alpha-4 chain antibody sodium/potassium-transporting ATPase beta-1 chain antibody Sodium/potassium-transporting ATPase subunit alpha-1 antibody sodium/potassium-transporting ATPase subunit alpha-4 antibody
- Purification：
- ProA affinity purified
- Applications：
- WB, IP, IF, IHC(P)
- Background：
- The ubiquitously expressed sodium/potassium-ATPase (Na+/K+-ATPase) exists as an oligomeric plasma membrane complex that couples the hydrolysis of one molecule of ATP to the importation of three Na+ ions and two K+ ions against their respective electrochemical gradients. As a member of the P-type family of ion motives, Na+/K+-ATPase plays a critical role in maintaining cellular volume, resting membrane potential and Na+-coupled solute transport. Multiple isoforms of three subunits, α, β and γ, comprise the Na+/K+-ATPase oligomer. The α subunit contains the binding sites for ATP and the cations; the glycosylated β subunit ensures correct folding and membrane insertion of the α subunits. The small γ subunit co-localizes with the α subunit in nephron segments, where it increases the affinity of Na+/K+-ATPase for ATP. The β subunit, but not the γ subunit, is essential for normal activity of Na+/K+-ATPase.
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