Product Datasheet  
Mst3 Antibody  
Catalog Number: 48317  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q9Y6E0
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Amino acids 275-393 of MST-3 of human origin.
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:100-1:1,000


    IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
  • other_names：  
  • epididymis secretory protein Li 95 antibody
    HEL-S-95 antibody
    Mammalian STE20 like protein kinase 3 antibody
    Mammalian STE20-like protein kinase 3 antibody
    Mammalian STE20-like protein kinase 3 C-terminal antibody
    Mammalian STE20-like protein kinase 3 N-terminal antibody
    Mammalian sterile 20-like 3 antibody
    MST-3 antibody
    MST3/C antibody
    MST3/N antibody
    MST3B antibody
    serine threonine kinase 24 antibody
    Serine/threonine kinase 24 (Ste20, yeast homolog) antibody
    Serine/threonine-protein kinase 24 12 kDa subunit antibody
    Serine/threonine-protein kinase 24 antibody
    STE20 homolog yeast antibody
    STE20 like kinase MST3 antibody
    STE20-like kinase MST3 antibody
    Stk24 antibody
    STK24_HUMAN antibody
    STK3 antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IP, IF
  • Background：  
  • Sterile-20 (STE20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cytosolic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to STE20 are divided into two groups, the PAK subfamily and the GCK subfamily. The PAK subfamily members contain a C-terminal catalytic domain and an N-terminal regulatory domain with a p21Rac/Cdc42-binding site, and these kinases can activate both p38 MAPK and JNK. The GCK subfamily members contain a C-terminal regulatory domain and an N-terminal catalytic domain, and they have diverse roles in many pathways, including the activation of ERK, JNK, p38 MAPK, and caspase-3. The mammalian STE20-like kinases (MST kinases, also known as Ksr proteins) are members of the GCK subfamily. Ksr-1 and Ksr-2 (also known as MST-2 and MST-1, respectively) are both direct substrates of caspase-3 that accelerate caspase-3 activation. MST-3 is ubiquitously expressed in mammalian tissue and can phosphorylate exogenous substrates as well as itself. MST-4 is highly expressed in placenta, thymus, and peripheral blood leukocytes, and it specifically activates ERK.



 
© Signalway Biotechnology All Rights Reserved.