Product Datasheet  
MKP-3 Antibody  
Catalog Number: 48316  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q16828
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:100-1:1,000
    IHC: 1:50-1:500

    IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
  • other_names：  
  • Dual specificity phosphatase 6 antibody
    Dual specificity phosphatase 6 isoform a antibody
    Dual specificity protein phosphatase 6 antibody
    Dual specificity protein phosphatase PYST1 antibody
    DUS6_HUMAN antibody
    DUSP 6 antibody
    DUSP 6a antibody
    Dusp6 antibody
    DUSP6a antibody
    HH19 antibody
    MAP kinase phosphatase 3 antibody
    Mitogen activated protein kinase phosphatase 3 antibody
    Mitogen-activated protein kinase phosphatase 3 antibody
    MKP 3 antibody
    MKP-3 antibody
    MKP3 antibody
    PYST 1 antibody
    PYST1 antibody
    Serine/threonine specific protein phosphatase antibody
    hide
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IP, IF, IHC(P)
  • Background：  
  • Mitogen-activated protein (MAP) kinases are a large class of proteins involved in signal transduction pathways that are activated by a range of stimuli and mediate a number of physiological and pathological changes in the cell. Dual specificity phosphatases (DSPs) are a subclass of the protein tyrosine phosphatase (PTP) gene superfamily, which are selective for dephosphorylating critical phosphothreonine and phosphotyrosine residues within MAP kinases. DSP gene expression is induced by a host of growth factors and/or cellular stresses, thereby negatively regulating MAP kinase superfamily members including MAPK/ERK, SAPK/JNK and p38. The members of the dual-specificity phosphatase protein family include MKP-1/CL100 (3CH134), VHR, PAC1, MKP-2, hVH-3 (B23), hVH-5, MKP-3, MKP-X, and MKP-4. Human MKP-3 maps to chromosome 12q21.33 and encodes a 381 amino acid protein that specifically inactivates members of the ERK family and is expressed in a variety of tissues with the highest levels in heart and pancreas.



 
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