Product Datasheet  
IL17 Antibody  
Catalog Number: 48308  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q16552
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:100-1:1,000


    IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
  • other_names：  
  • CTLA 8 antibody
    CTLA-8 antibody
    CTLA8 antibody
    Cytotoxic T lymphocyte associated antigen 8 antibody
    Cytotoxic T lymphocyte associated protein 8 antibody
    Cytotoxic T lymphocyte associated serine esterase 8 antibody
    Cytotoxic T-lymphocyte-associated antigen 8 antibody
    IL 17A antibody
    IL-17 antibody
    IL-17A antibody
    IL17 antibody
    IL17_HUMAN antibody
    Il17a antibody
    Interleukin 17 (cytotoxic T lymphocyte associated serine esterase 8) antibody
    Interleukin 17A antibody
    Interleukin-17A antibody
    Interleukin17 antibody
    Interleukin17A antibody
    OTTHUMP00000016597 antibody
    OTTMUSP00000046003 antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IP, IF
  • Background：  
  • Cytokines are small, soluble proteins with pleiotropic effects on a variety of cell types. Cytokines have a regulatory function over the immune system and mediate aspects of inflammatory response. They exert their biological effects through the binding of membrane-bound receptors which, in turn, initiate signal transduction cascades and elicit physiological changes in their target cell. Interleukin-17 (IL-17) and its cognate receptor, IL-17R, are an example of such a cytokine receptor pair. Originally identified as a rodent cDNA termed CTLA8, IL-17 is capable of inducing the secretion of IL-6 and IL-8 and augmenting the expression of ICAM-1 in human fibroblast cultures. The IL-17 protein exhibits a striking degree of homology with the HSV13 protein which mimics its function. The IL-17 receptor is a type I transmembrane protein 864 amino acids in length, that is highly expressed in spleen and kidney.



 
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