Product Datasheet  
IFN alpha R1 Antibody  
Catalog Number: 48307  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P33896
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • The extracellular domain of IFN-αR1 of mouse origin.
  • reactivity：  
  • Ms
  • appl_detail：  
  • WB: 1:100-1:1,000


    IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
    FC: 1 μg per 1 x 106 cells
  • other_names：  
  • Alpha type antiviral protein antibody
    Antiviral protein, alpha-type antibody
    Antiviral protein, beta-type antibody
    AVP antibody
    Beta type antiviral protein antibody
    CRF2-1 antibody
    Cytokine receptor class-II member 1 antibody
    Cytokine receptor family 2 member 1 antibody
    IFN alpha REC antibody
    IFN alpha receptor antibody
    IFN alpha/beta Receptor alpha antibody
    IFN beta receptor antibody
    IFN Interferon-beta receptor antibody
    IFN-alpha/beta receptor 1 antibody
    IFN-R-1 antibody
    IFNAR antibody
    Ifnar1 antibody
    IFNBR antibody
    IFRC antibody
    INAR1_HUMAN antibody
    Interferon (alpha beta and omega) receptor 1 antibody
    interferon alpha and beta receptor subunit 1 antibody
    Interferon alpha/beta receptor 1 antibody
    Interferon alpha/beta receptor alpha chain antibody
    Interferon beta receptor 1 antibody
    interferon receptor 1 antibody
    Interferon-alpha receptor antibody
    Type I interferon receptor 1 antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IP, FCM
  • Background：  
  • The type I interferons (IFNs), ? and , are a group of structurally and functionally related proteins that are induced by either viruses or double stranded RNA and defined by their ability to confer an antiviral state in cells. The ? and IFNs appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN?) binds to a distinct receptor. The latter protein, IFN-?R, is only weakly responsive to type I interferons in contrast to IFN-?/R, which binds to and responds effectively to IFN- and to several of the IFN-? subtypes. Moreover, IFN-?/R is physically associated with the cytoplasmic tyrosine kinase JAK1 and thus, in addition to ligand binding, appears to be functionally involved in signal transduction. IFN-?R1 is a receptor for IFN-?/ and is present as the full chain (IFN-?R1a) and as a splice-variant (IFN-?R1). The IFN-? receptor complex consists of an alpha subunit (IFN-?R?) and a beta subunit that is 332 amino acids in length (mouse) and 337 amino acids in length (human).



 
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