Product Datasheet  
HLA E Antibody  
Catalog Number: 48304  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:P13747
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant HLA-E of human origin
  • reactivity：  
  • Hu
  • appl_detail：  
  • WB: 1:100-1:1,000


    IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) FCM: 1 μg per 1 x 106 cells
    FC: 1 μg per 1 x 106 cells
  • other_names：  
  • HLA class I histocompatibility antigen E alpha chain antibody
    EA1.2 antibody
    EA2.1 antibody
    HLA 6.2 antibody
    HLA class I histocompatibility antigen alpha chain E antibody
    HLA class I histocompatibility antigen E alpha chain precursor antibody
    HLA class I histocompatibility antigen E alpha chain precursor antibody
    HLA6.2 antibody
    HLAE antibody
    Lymphocyte antigen antibody
    Major histocompatibility complex class I E antibody
    MHC antibody
    MHC class I antigen E antibody
    MHC HLA E alpha 1 antibody
    MHC HLA E alpha 2.1 antibody
    QA1 antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IP, FCM
  • Background：  
  • Major histocompatibility complex (MHC) molecules, which include human leukocyte antigens (HLAs), form an integral part of the immune response system. They are cell surface receptors that bind foreign peptides and present them to cytotoxic T lymphocytes (CTLs). MHC class I molecules consist of two polypeptide chains, an α or heavy chain and a non-covalently associated pro- tein, β-2-Microglobulin. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. HLA-A is a MHC class I heavy chain molecule that plays a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. HLA-B and HLA-C are proteins encod- ed by closely related genes that also exist in the MHC class I. HLA-E belongs to the HLA class I heavy chain paralog. HLA-E is a heterodimer consisting of a heavy chain and a light chain; the heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules.



 
© Signalway Biotechnology All Rights Reserved.