Product Datasheet  
Hepatitis B Virus X antigen Antibody  
Catalog Number: 48299  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Mouse
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:Q4R1S1
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • peptide
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB: 1:100-1:1,000


    IP: 1C2 μg per 100C500 μg of total protein (1 ml of cell lysate).
  • other_names:  
  • Purification:  
  • ProA affinity purified
  • Specificity:  
  • Applications:  
  • Background:  
  • Hep B (hepatitus B) virus is a member of the Hepadnavirus family that causes an inflammation of the liver, vomiting, jaundice and, sometimes, death. Three major antigens make up different parts of the Hep B virus (HBV): surface antigen (Hep B sAg), an envelope glycoprotein found as membranous aggregates in the sera of individuals infected with HBV; e-antigen (Hep B eAg), which is typically associated with much higher rates of viral replication; and core antigen (Hep B cAg), which encloses the viral genome and makes up the assembled and unassembled variants of the capsid protein. Hep B cAg and Hep B eAg are used primarily in HBV diagnosis, whereas Hep B sAg is used for HBV prevention in vaccines. Hep B viral antigens are primarily expressed in liver. Hep B xAg represents the Hep B virus X protein which contributes to human hepatocellular carcinoma metastasis by the upregulation of matrix metalloproteinases.



 
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