Product Datasheet
Hepatitis B Virus X antigen Antibody
Catalog Number: 48299
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q4R1S1
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- appl_detail:
- WB: 1:100-1:1,000
IP: 1C2 μg per 100C500 μg of total protein (1 ml of cell lysate).
- Purification:
- ProA affinity purified
- Background:
- Hep B (hepatitus B) virus is a member of the Hepadnavirus family that causes an inflammation of the liver, vomiting, jaundice and, sometimes, death. Three major antigens make up different parts of the Hep B virus (HBV): surface antigen (Hep B sAg), an envelope glycoprotein found as membranous aggregates in the sera of individuals infected with HBV; e-antigen (Hep B eAg), which is typically associated with much higher rates of viral replication; and core antigen (Hep B cAg), which encloses the viral genome and makes up the assembled and unassembled variants of the capsid protein. Hep B cAg and Hep B eAg are used primarily in HBV diagnosis, whereas Hep B sAg is used for HBV prevention in vaccines. Hep B viral antigens are primarily expressed in liver. Hep B xAg represents the Hep B virus X protein which contributes to human hepatocellular carcinoma metastasis by the upregulation of matrix metalloproteinases.
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