Product Datasheet
ALCAM/CD166 Antibody
Catalog Number: 48272
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:Q13740
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- appl_detail:
- WB: 1:100-1:1,000
IHC: 1:50-500
IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
- other_names:
- Activated leukocyte cell adhesion molecule antibody ALCAM antibody ALCAM protein antibody CD 166 antibody CD166 antibody CD166 antigen antibody CD166_HUMAN antibody FLJ3851 antibody FLJ38514 antibody MEMD antibody MGC71733 antibody
- Purification:
- ProA affinity purified
- Applications:
- WB, IP, IF, IHC(P)
- Background:
- Activated leukocyte cell adhesion molecule (ALCAM), expressed on activated leukocytes, T cells, B cells and monocytes, is a member of the immunoglobulin superfamily (IgSF) and identified as a CD6 ligand. CD6 is a type I membrane protein in the scavenger receptor cysteine rich protein superfamily that acts in T cell adhesion and costimulation. ALCAM mediates thymocyte-thymic epithelial cell adhesion via homophilic (ALCAM-ALCAM) and heterophilic (ALCAMCD6) interactions involving a previously undescribed protein-protein interaction between a member of the scavenger receptor cysteine rich protein superfamily and the immunoglobulin superfamily.
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