Product Datasheet  
CD137 Antibody  
Catalog Number: 48126  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:Q07011
  • Form of Antibody：  
  • 1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant protein
  • reactivity：  
  • Hu, Ms, Rt
  • appl_detail：  
  • WB: 1:500
    IHC: 1:50-1:200
    ICC: 1:100-1:500

    FC: 1:50-1:200
  • other_names：  
  • 4 1BB antibody
    4 1BB ligand receptor antibody
    4-1BB ligand receptor antibody
    4-1BB Ligand Receptor T Cell antibody
    4-1BB, mouse, homolog of antibody
    Antigen 4-1BB Homolog antibody
    CD 137 antibody
    CD137 antibody
    CD137 antigen antibody
    CDw137 antibody
    HLDA VI antibody
    Homolog of mouse 4 1BB antibody
    ILA antibody
    induced by lymphocyte activation (ILA) antibody
    Induced by lymphocyte activation antibody
    Interleukin activated receptor homolog of mouse Ly63 antibody
    Ly63, mouse, homolog of antibody
    MGC2172 antibody
    OTTHUMP00000044294 antibody
    Receptor protein 4 1BB antibody
    T cell antigen 4 1BB homolog antibody
    T cell antigen ILA antibody
    T-cell antigen 4-1BB homolog antibody
    T-cell antigen ILA antibody
    TNF receptor superfamily member 9 antibody
    TNFRSF9 antibody
    TNR9_HUMAN antibody
    Tumor necrosis factor receptor superfamily member 9 antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, IHC, ICC, FC
  • Background：  
  • CD137, also designated ILA and 4-1BB in mouse, belongs to the tumor necrosis factor receptor family and delivers a costimulatory signal to T lymphocytes. CD137 is expressed on activated T cells and binds an inducible ligand that is found on B cells, macrophages, and dendritic cells. Interactions between CD137 and its ligand are involved in antigen presentation and the generation of cytotoxic T cells. Crosslinking of the CD137 ligand induces apoptosis in resting lymphocytes. In contrast, CD137 regulates peripheral monocyte survival by inducing a cytokine release profile, and is mediated by M-CSF and to a lesser extent by granulocyte-macrophage colony-stimulating factor and IL-3. Soluble forms of CD137 are found in sera from patients with rheumatoid arthritis and may provide a negative control mechanism for immune responses.



 
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