Product Datasheet  
AKR7A2 Antibody  
Catalog Number: 48114  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#:O43488
  • Form of Antibody：  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • peptide
  • reactivity：  
  • Hu, zebrafish
  • appl_detail：  
  • WB: 1:1,000-1:2,000

    ICC: 1:200

  • other_names：  
  • AFAR antibody
    AFAR1 antibody
    AFB1 aldehyde reductase 1 antibody
    AFB1 AR1 antibody
    AFB1-AR 1 antibody
    AFB1AR1 antibody
    Aflatoxin aldehyde reductase antibody
    Aflatoxin B1 aldehyde reductase member 2 antibody
    Aflatoxin beta1 aldehyde reductase antibody
    Aiar antibody
    AKR7 antibody
    Akr7a2 antibody
    Aldo keto reductase family 7 antibody
    Aldo keto reductase family 7 member A2 aflatoxin aldehyde reductase antibody
    Aldo keto reductase family 7 member A2 antibody
    Aldo keto reductase family 7, member A2 (aflatoxin aldehyde reductase) antibody
    Aldoketoreductase 7 antibody
    ARK72_HUMAN antibody
    SSA reductase antibody
    Succinic semialdehyde reductase antibody
  • Purification：  
  • ProA affinity purified
  • Specificity：  
  • Applications：  
  • WB, ICC, IHC
  • Background：  
  • Aflatoxin B1 aldehyde reductase member 2 is an enzyme that in humans is encoded by the AKR7A2 gene. It catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate and may have an important role in producing the neuromodulator gamma-hydroxybutyrate (GHB). AKR7A2 has broad substrate specificity and NADPH-dependent aldehyde reductase activity towards 2-carboxybenzaldehyde, 2-nitrobenzaldehyde and pyridine-2-aldehyde (in vitro). AKR7A2 can reduce 1,2-naphthoquinone and 9,10-phenanthrenequinone (in vitro) and reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It may be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.



 
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