Product Datasheet
UFO Antibody
Catalog Number: 48103
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P30530
- Form of Antibody:
- 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- Immunogen:
- Recombinant protein within human UFO 1-150 aa.
- appl_detail:
- WB: 1:500
ICC: 1:200-1:500
- other_names:
- Adhesion related kinase antibody
AI323647 antibody
Ark antibody
Axl antibody
AXL oncogene antibody
AXL receptor tyrosine kinase antibody
AXL transforming gene antibody
AXL transforming sequence/gene antibody
EC 2.7.10.1 antibody
JTK11 antibody
Oncogene AXL antibody
Tyro7 antibody
Tyrosine protein kinase receptor UFO antibody
Tyrosine-protein kinase receptor UFO antibody
UFO antibody
UFO_HUMAN antibody
- Purification:
- ProG affinity purified
- Background:
- Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. AXL receptor tyrosine kinase has been shown to interact with TENC1.Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.
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