Product Datasheet  
UFO Antibody  
Catalog Number: 48103  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Mouse
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#:P30530
  • Form of Antibody:  
  • 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • Recombinant protein within human UFO 1-150 aa.
  • reactivity:  
  • Hu
  • appl_detail:  
  • WB: 1:500

    ICC: 1:200-1:500

  • other_names:  
  • Adhesion related kinase antibody
    AI323647 antibody
    Ark antibody
    Axl antibody
    AXL oncogene antibody
    AXL receptor tyrosine kinase antibody
    AXL transforming gene antibody
    AXL transforming sequence/gene antibody
    EC 2.7.10.1 antibody
    JTK11 antibody
    Oncogene AXL antibody
    Tyro7 antibody
    Tyrosine protein kinase receptor UFO antibody
    Tyrosine-protein kinase receptor UFO antibody
    UFO antibody
    UFO_HUMAN antibody
  • Purification:  
  • ProG affinity purified
  • Specificity:  
  • Applications:  
  • WB, ICC
  • Background:  
  • Tyrosine-protein kinase receptor UFO is an enzyme that in humans is encoded by the AXL gene. The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, the Axl protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation. This receptor can also mediate cell aggregation by homophilic binding. Axl is a chronic myelogenous leukemia-associated oncogene and also associated with colon cancer and melanoma. AXL receptor tyrosine kinase has been shown to interact with TENC1.Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival.



 
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