Product Datasheet
kinase D-interacting substrate 220 Antibody
Catalog Number: 48066
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:
- Form of Antibody:
- 1*TBS (pH7.4),0.5%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
- appl_detail:
- WB: 1:1,000-1:10,000
IHC: 1:50
ICC: 1:100
- Purification:
- ProA affinity purified
- Applications:
- WB, ICC, IHC
- Background:
- Kinase D-interacting substrate 220 (Kidins220), also known as ARMS (ankyrin-rich membrane spanning) is an integral plasma membrane protein predominantly expressed in brain and neurons that presents a polarized location in neural cells, concentrating at the tip of extending neurites and in plasma membrane micro-domains corresponding to lipid rafts. The primary amino acid sequence of Kidins220 reveals 11 ankyrin repeats, 4 trans-membrane domains, a proline-rich region, a sterile-α motif (or SAM) domain, and a type I postsynaptic density-95/discs large/zonula occludens-1 (PDZ)-binding motif at the very C-terminus.
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