Product Datasheet  
PCNA Mouse Monoclonal Antibody  
Catalog Number: 37978  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Mouse
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot:P12004
    Gene ID:5111
  • Form of Antibody:  
  • Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage:  
  • Store at -20˚C
  • Immunogen:  
  • reactivity:  
  • Hu Ms
  • appl_detail:  
  • WB dilution: 1:5000
    IHC dilution: 1:200

    IF dilution:1:200
  • other_names:  
  • Purification:  
  • Affinity purification using immunogen.
  • Specificity:  
  • Antibody can detect endogenous?PCNA protein.
  • Applications:  
  • WB,IHC,IF
  • Background:  
  • PCNA is a marker for cells in early G1 phase and S phase of the cell cycle. It is found in the nucleus and is a cofactor of DNA polymerase delta. PCNA acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, PCNA is ubiquitinated and is involved in the RAD6 dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for PCNA. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.



 
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