Product Datasheet  
D-3-phosphoglycerate dehydrogenase Polyclonal Antibody  
Catalog Number: 42388  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O43175
  • Form of Antibody：  
  • Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant human D-3-phosphoglycerate dehydrogenase protein
  • reactivity：  
  • Hu
  • appl_detail：  
  • Western blotting: 1:500 - 1:1000
    Immunohistochemistry: 1:20 - 1:200
  • other_names：  
  • 3-PGDH??PGDH3??PHGDH
  • Purification：  
  • Caprylic Acid Ammonium Sulfate Precipitation purified
  • Specificity：  
  • The antibody detects endogenous level of total D-3-phosphoglycerate dehydrogenase polyclonal antibody.
  • Applications：  
  • WB IHC
  • Background：  
  • PHGDH or 3-phosphoglycerate dehydrogenase is an enzyme belonging to the D-isomer specific 2-hydroxyacid dehydrogenase family. It catalysis the reaction 3-phosphoglycerate + NAD+ = 3-phosphonooxypyruvate + NADH during L-serine biosynthesis. Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency (PHGDH deficiency). It is characterized by congenital microcephaly, psychomotor retardation and seizures.



 
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