Product Datasheet
Galectin-3 Polyclonal Antibody
Catalog Number: 42237
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: P17931
- Form of Antibody:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Immunogen:
- Recombinant human Galectin-3 protein
- appl_detail:
- Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200
- other_names:
- 35 kDa lectin, Carbohydrate-binding protein 35, Galactose-specific lectin 3, Galactoside-binding protein, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen, LGALS3 , MAC2
- Purification:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Specificity:
- The antibody detects endogenous level of total Galectin-3 polyclonal antibody.
- Background:
- Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis By similarity. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.
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