Product Datasheet  
Kynurenine 3-monooxygenase Polyclonal Antibody  
Catalog Number: 42233  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Rabbit
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Swiss-Prot#: O15229
  • Form of Antibody：  
  • Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • Recombinant human Kynurenine 3-monooxygenase protein(1-486aa)
  • reactivity：  
  • Hu
  • appl_detail：  

  • Immunohistochemistry: 1:20 - 1:200
  • other_names：  
  • Kynurenine 3-hydroxylase, KMO
  • Purification：  
  • Caprylic Acid Ammonium Sulfate Precipitation purified
  • Specificity：  
  • The antibody detects endogenous level of total Kynurenine 3-monooxygenase polyclonal antibody.
  • Applications：  
  • IHC
  • Background：  
  • Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract.



 
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