Product Datasheet
Histone H2A.J Polyclonal Antibody
Catalog Number: 42198
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#: Q9BTM1
- Form of Antibody:
- Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
- Immunogen:
- Recombinant Human Histone H2A.J protein
- appl_detail:
- Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200
- Purification:
- Caprylic Acid Ammonium Sulfate Precipitation purified
- Specificity:
- The antibody detects endogenous level of total Histone H2A.J polyclonal antibody.
- Background:
- Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
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