Product Datasheet
Insulin Degrading Enzyme Mouse Monoclonal Antibody
Catalog Number: 38040
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Form of Antibody:
- Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- appl_detail:
- WB dilution: 1:1000~1:2000
IHC dilution:1:50-300
IF dilution:1:200
- Purification:
- Affinity purification using immunogen.
- Specificity:
- IDE Mouse Monoclonal antibody detects endogenous IDE proteins.
- Background:
- Insulin Degrading Enzyme (IDE) is a large zinc-binding protease of the M16A metalloprotease subfamily known to cleave multiple short polypeptides that vary considerably in sequence. IDE was first identified by its ability to degrade the B chain of the hormone insulin. This activity was observed over fifty years ago, though the enzyme specifically responsible for B chain cleavage was identified more recently.
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