Product Datasheet  
Myosin Heavy Chain Mouse Monoclonal Antibody  
Catalog Number: 38013  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Form of Antibody：  
  • Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • Store at -20˚C
  • Immunogen：  
  • reactivity：  
  • Hu Ms Rt Dm Nematode
  • appl_detail：  
  • IF dilution: 1:100
  • other_names：  
  • Purification：  
  • Affinity purification using immunogen.
  • Specificity：  
  • The Myosin Heavy Chain Mouse Monoclonal antibody detects endogenous MHC proteins.
  • Applications：  
  • IF
  • Background：  
  • Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies.



 
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