Product Datasheet
CD23 Mouse Monoclonal Antibody
Catalog Number: 38004
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P30273
- Form of Antibody:
- Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- appl_detail:
- IHC dilution: 1:200
IF dilution:1:50-200
- other_names:
- Fc fragment of IgE, high affinity I, receptor for; Fc-epsilon RI-gamma; FCER1G; FCERG
- Purification:
- Affinity purification using immunogen.
- Specificity:
- The CD23 antibody detects endogenous CD23 proteins.
- Background:
- The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils.
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