Product Datasheet
ErbB-2/HER-2 Mouse Monoclonal Antibody
Catalog Number: 37997
Technical:tech@swbio.com
Information:info@swbio.com
Description
- Swiss-Prot No.:
- Swiss-Prot#:P04626
- Form of Antibody:
- Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
- appl_detail:
- WB dilution: 1:2000~1:4000
IHC dilution: 1:200
IF dilution:1:200
- other_names:
- c-erb B2/neu protein; CD340; erbB-2; ERBB2; HER-2; HER-2/neu; HER2; herstatin; Metastatic lymph node gene 19 protein; MLN 19;
- Purification:
- Affinity purification using immunogen.
- Specificity:
- The ErbB-2/HER-2 Mouse Monoclonal antibody detects endogenous ErbB-2/HER-2 proteins.
- Background:
- ErbB 2 is a receptor tyrosine kinase of the ErbB 2 family. It is closely related instructure to the epidermal growth factor receptor. ErbB 2 oncoprotein is detectable in a proportion of breast and other adenocarconomas, as well as transitional cell carcinomas. In the case of breast cancer, expression determined by immunohistochemistry has been shown to be associated with poor prognosis.
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