Product Datasheet  
WDR77 Monoclonal Antibody  
Catalog Number: 27213  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species：  
  • Mouse
  • Amount：  
  • 100μgμg
  • Swiss-Prot No.：  
  • Uniprot: Q9BQA1

    Gene ID: 79084

  • Form of Antibody：  
  • Purified mouse monoclonal in PBS(pH 7.4) containing with 0.02% sodium azide and 50% glycerol.
  • Storage：  
  • store at -20˚C
  • Immunogen：  
  • Purified recombinant human WDR77 protein fragments expressed in E.coli.
  • reactivity：  
  • Hu Ms Rt
  • appl_detail：  

  • Western blotting: 1:1000

    Immunocytochemistry: 1:100
  • other_names：  
  • 2610312E17Rik; Androgen receptor cofactor p44; C79984; HKMT1069; MEP 50; MEP-50; MEP50; MEP50_HUMAN; Methylosome protein 50; MGC2722; Nbla10071; p44; p44/Mep50; RGD1310479; RP11 552M11.3; WD repeat containing protein 77; WD repeat domain 77;
  • Purification：  
  • Affinity purified
  • Specificity：  
  • This antibody detects endogenous levels of WDR77 and does not cross-react with related proteins.
  • Applications：  
  • WB ICC
  • Background：  

  •  Non-catalytic component of the 20S PRMT5-containing methyltransferase complex,which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones.This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles.Might play a role in transcription regulation.The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4),methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.




 
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