Product Datasheet  
ARPC1B antibody  
Catalog Number: 40409  
Technical:tech@swbio.com  
Information:info@swbio.com  
Description  
  • host_species:  
  • Rabbit
  • Amount:  
  • 100μgμg
  • Swiss-Prot No.:  
  • Swiss-Prot#: O43897
    NCBI Protein#: BC002562
  • Form of Antibody:  
  • pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • Storage:  
  • Store at -20˚C/1 year
  • Immunogen:  
  • Fusion protein of human ARPC1B
  • reactivity:  
  • Hu, Ms, Rt
  • appl_detail:  
  • WB dilution:1:500-1:2000
    IHC dilution:1:50-1:100
  • other_names:  
  • ARC41; PLTEID; p40-ARC; p41-ARC
  • Purification:  
  • Antigen affinity purification
  • Specificity:  
  • Applications:  
  • WB, IHC
  • Background:  
  • This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.



 
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